The global indoleamine 2,3 dioxygenase 1 market is anticipated to grow at a substantial CAGR during the forecast period. Indoleamine 2,3 dioxygenase 1 (IDO) is an enzyme that catalyzes the degradation of the essential amino acid tryptophan in many types of cells including dendritic cells (DCs), which has been proposed to be an authentic regulator of immune responses. The heme enzyme in indoleamine 2,3 dioxygenase 1 (IDO1) catalyzes the oxidation of L-tryptophan, which is the first step of the kynurenine pathway. IDO1 is widely being used for cancer immune escape and overexpression of IDO1 has been linked to poor prognosis in many malignancies. Thus, the increased prevalence of cancer across the globe is one of the key factors which is bolstering the growth of the market.
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Impact of COVID-19 on Global Indoleamine 2,3 Dioxygenase 1 Market
COVID-19 has had a major influence on the global indoleamine 2,3 dioxygenase 1 market. Healthcare professionals working at the US-based Dana Farber Cancer Institute published a paper in Cancer Connect in 2020, which concluded that during COVID-19, there was a 46% decline in diagnoses of the six most frequent cancer types that including breast, colorectal, lung, pancreatic, gastric, and esophageal cancers. In addition, the Centers for Disease Control and Prevention (CDC) and many medical professional organizations advised that cancer screening and other health-prevention services, as well as elective surgeries, be postponed unless the risks outweighed the benefits and that hospitals be prepared to treat COVID-19 patients. As a result of COVID-19, the overall cancer therapeutics market had been damaged, further hindering the growth of the indoleamine 2,3 dioxygenase 1 market.
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Segmental Outlook
The global indoleamine 2,3 dioxygenase 1 market is segmented based on type and application. Based on type, the market is segmented into BMS-986205, dcellvax, epacadostat, F-001287, galanal, and others. Based on application the market is segmented into alopecia, cervical cancer, gastric cancer, glioma, and others. The above-mentioned segments can be customized as per the requirements.
by Type (BMS-986205, Dcellvax, Epacadostat, F-001287, Galanal, and Others), and
by Application (Alopecia, Cervical Cancer, Gastric Cancer, Glioma, and Others)
Market Players Outlook
The major companies serving the global Indoleamine 2,3 Dioxygenase 1 market include Bristol-Myers Squibb, Merck KGaA, BirchBioMed Inc., Genentech Inc., F. Hoffmann-La Roche Ltd., and others. To enhance their market share, industry participants are employing several critical techniques. For instance, The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency has recommended that nivolumab (Opdivo) and ipilimumab (Yervoy) be approved for use in the frontline treatment of adult patients with unresectable advanced, recurrent, or metastatic esophageal squamous cell carcinoma (ESCC) with a PD-L1 expression of 1% or higher.1
The Report Covers
Market value data analysis of 2021 and forecast to 2028.
Annualized market revenues ($ million) for each market segment.
Country-wise analysis of major geographical regions.
Key companies operating in the global indoleamine 2,3 dioxygenase 1 market. Based on the availability of data, information related to new product launches, and relevant news is additionally available in the report.
Analysis of business strategies by identifying the key market segments positioned for strong growth in the future.
Analysis of market entry and market expansion strategies.
Competitive strategies by identifying ‘who-stands-where’ in the market.
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